Alterations in vitamin A and thyroid hormone status in anorexia nervosa and associated disorders.
Am J Clin Nutr
; 42(6): 1183-91, 1985 Dec.
Article
em En
| MEDLINE
| ID: mdl-3865529
ABSTRACT
Vitamin A and thyroid hormone status was investigated in 27 patients with anorexia nervosa. Subjects were divided into three groups based on eating behavior and serum carotene concentrations anorexic (dietary restriction), normal carotene; anorexic, elevated serum carotene; bulimic, elevated serum carotene. All bulimic subjects fulfilling selection criteria were hypercarotenemic (weight loss and reduced metabolic rate). Data were compared to normal healthy volunteers. Serum retinol and retinol-binding protein levels were normal in all subjects whereas retinyl esters were elevated in the hypercarotenemic groups. Hypercarotenemia was primarily a result of elevation of vitamin A active carotenoids, especially beta-carotene. Diet was excluded from the etiology of hypercarotenemia. Thyroid hormones T4 and T3 were significantly depressed in hypercarotenemic groups and rT3 increased. A concomitant alteration in vitamin-hormone status is observed with progressive metabolic alterations low T3, T4, and elevated retinyl esters in subjects with the hypercarotenemia associated with anorexia nervosa.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hormônios Tireóideos
/
Vitamina A
/
Anorexia Nervosa
/
Hiperfagia
/
Transtornos da Alimentação e da Ingestão de Alimentos
Tipo de estudo:
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article