The genetics of niche-specific behavioral tendencies in an adaptive radiation of cichlid fishes.
Science
; 384(6694): 470-475, 2024 Apr 26.
Article
em En
| MEDLINE
| ID: mdl-38662824
ABSTRACT
Behavior is critical for animal survival and reproduction, and possibly for diversification and evolutionary radiation. However, the genetics behind adaptive variation in behavior are poorly understood. In this work, we examined a fundamental and widespread behavioral trait, exploratory behavior, in one of the largest adaptive radiations on Earth, the cichlid fishes of Lake Tanganyika. By integrating quantitative behavioral data from 57 cichlid species (702 wild-caught individuals) with high-resolution ecomorphological and genomic information, we show that exploratory behavior is linked to macrohabitat niche adaptations in Tanganyikan cichlids. Furthermore, we uncovered a correlation between the genotypes at a single-nucleotide polymorphism upstream of the AMPA glutamate-receptor regulatory gene cacng5b and variation in exploratory tendency. We validated this association using behavioral predictions with a neural network approach and CRISPR-Cas9 genome editing.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Comportamento Animal
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Adaptação Fisiológica
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Receptores de AMPA
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Ciclídeos
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Comportamento Exploratório
Limite:
Animals
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article