Two new oleanane triterpenes from Maytenus hookeri.
J Asian Nat Prod Res
; 26(7): 803-811, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38721701
ABSTRACT
Two new triterpenes mayteneri A (1), mayteneri B (2), and seven known compounds (3-9) were isolated from stems of Maytenus hookeri Loes. The chemical structures of compounds 1 and 2 were established by 1D, 2D NMR, HRESIMS analysis, and calculating electronic circular dichroism (ECD). The structures of known compounds 3-9 were determined by comparison of their spectral with those reported. Compounds 4-7 showed significant inhibitory activity for NLRP3 inflammasome, with the IC50 values of 2.36-3.44 µM.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Oleanólico
/
Maytenus
Limite:
Animals
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article