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Should we review our prophylaxis approach for increased antibiotic resistance in transrectal prostate biopsy?
Altunsoy, Adalet; Coser, Seref; Kemirtlek, Nizamettin; Aykanat, Ibrahim Can; Balci, Melih; Bodur, Hürrem; Tuncel, Altug.
Afiliação
  • Altunsoy A; University of Health Science, Ankara City Hospital, Infectious Diseases and Clinical Microbiology. Ankara, Turkey.
  • Coser S; Department of Urology, University of Health Sciences, School of Medicine, Ankara City Hospital, Ankara, Turkey.
  • Kemirtlek N; Ankara City Hospital, Infectious Diseases and Clinical Microbiology. Ankara, Turkey.
  • Aykanat IC; Department of Urology, Koç University Hospital, Istanbul, Turkey.
  • Balci M; Department of Urology, University of Health Sciences, School of Medicine, Ankara City Hospital, Ankara, Turkey.
  • Bodur H; University of Health Science, Ankara City Hospital, Infectious Diseases and Clinical Microbiology. Ankara, Turkey.
  • Tuncel A; Department of Urology, University of Health Sciences, School of Medicine, Ankara City Hospital, Ankara, Turkey.
J Infect Dev Ctries ; 18(4): 595-599, 2024 Apr 30.
Article em En | MEDLINE | ID: mdl-38728642
ABSTRACT

INTRODUCTION:

This study aims to show the bacteriologic picture of acute prostatitis and bacteremia caused by infective agent after transrectal ultrasound-guided prostate biopsy (TRUSBx) and to determine the resistance rates of the infections in patients undergoing transrectal biopsy and to guide prophylaxis approach before biopsy.

METHODOLOGY:

The retrospective data of 935 patients who underwent TRUSBx between January 2010 to January 2019 were reviewed. Pre-biopsy urine cultures and antimicrobial susceptibility were obtained. Subsequently, patients admitted to the hospital with any complaint after biopsy were examined for severe infection complications.

RESULTS:

Of the 430 (61.7%) patients who underwent urine culture before the procedure, 45 (10.5%) had growth; 30 (66.7%) of the growing microorganisms were Escherichia coli. Twenty (44.4%) of all Gram-negative agents in pre-biopsy urine culture were susceptible to quinolone. Post TRUSBx bacteremia was present in 18.2%, urinary system infection in 83.6%, and hospitalization in 61.8% of 55 patients who were admitted to the hospital. In the isolated gram-negative microorganisms, fluoroquinolones resistance in urinary system infections was seen in 40% and bacteremia was seen in 70% of the cases. ESBL-producing Gram-negative bacteria were determined in 40% of infections in blood and 38.5% of urinary system infections in the post biopsy period in the current study.

CONCLUSIONS:

These high antibiotic resistance rates suggest that we better review our pre-procedure prophylaxis approaches.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Próstata / Bacteriemia / Antibioticoprofilaxia / Antibacterianos Limite: Aged / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Próstata / Bacteriemia / Antibioticoprofilaxia / Antibacterianos Limite: Aged / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article