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Evaluation of Acute and Convalescent Antibody Concentration Against Pneumococcal Capsular Polysaccharides for the Diagnosis of Pneumococcal Infection in Children with Community-Acquired Pneumonia.
Carter, Michael J; Shrestha, Sonu; O'Reilly, Peter; Gurung, Pallavi; Gurung, Meeru; Thorson, Stephen; Kandasamy, Rama; Voysey, Merryn; O'Mahony, Elizabeth; Kelly, Sarah; Ansari, Imran; Shah, Ganesh; Amatya, Puja; Tcherniaeva, Irina; Berbers, Guy; Murdoch, David R; Pollard, Andrew J; Shrestha, Shrijana; Kelly, Dominic F.
Afiliação
  • Carter MJ; Paediatric Intensive Care, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Shrestha S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford.
  • O'Reilly P; NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.
  • Gurung P; National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, Sydney, Australia.
  • Gurung M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford.
  • Thorson S; NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.
  • Kandasamy R; Oxford Vaccine Group, Department of Paediatrics, University of Oxford.
  • Voysey M; NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.
  • O'Mahony E; Pediatric Research Group, Patan Academy of Health Sciences, Patan, Kathmandu, Nepal.
  • Kelly S; Pediatric Research Group, Patan Academy of Health Sciences, Patan, Kathmandu, Nepal.
  • Ansari I; Pediatric Research Group, Patan Academy of Health Sciences, Patan, Kathmandu, Nepal.
  • Shah G; Discipline of Paediatrics and Child Health, School of Clinical Medicine, University of New South Wales.
  • Amatya P; National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, Sydney, Australia.
  • Tcherniaeva I; Oxford Vaccine Group, Department of Paediatrics, University of Oxford.
  • Berbers G; NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.
  • Murdoch DR; Oxford Vaccine Group, Department of Paediatrics, University of Oxford.
  • Pollard AJ; NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.
  • Shrestha S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford.
  • Kelly DF; NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom.
Pediatr Infect Dis J ; 43(2): e67-e70, 2024 Feb 01.
Article em En | MEDLINE | ID: mdl-38758207
ABSTRACT
We evaluated whether the quantification of IgG to pneumococcal capsular polysaccharides is an accurate diagnostic test for pneumococcal infection in children with pneumonia in Nepal. Children with pneumococcal pneumonia did not have higher convalescent, or higher fold change, IgG to pneumococcal polysaccharides than children with other causes of pneumonia. Caution is needed in interpreting antibody responses in pneumococcal infections.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Pneumocócica / Polissacarídeos Bacterianos / Streptococcus pneumoniae / Imunoglobulina G / Infecções Comunitárias Adquiridas / Anticorpos Antibacterianos Limite: Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Asia Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Pneumocócica / Polissacarídeos Bacterianos / Streptococcus pneumoniae / Imunoglobulina G / Infecções Comunitárias Adquiridas / Anticorpos Antibacterianos Limite: Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Asia Idioma: En Ano de publicação: 2024 Tipo de documento: Article