Association of gut dysbiosis with firstepisode psychosis (Review).
Mol Med Rep
; 30(1)2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38785152
ABSTRACT
The gutmicrobiotabrain axis is a complex bidirectional communication system linking the gastrointestinal tract to the brain. Changes in the balance, composition and diversity of the gutmicrobiota (gut dysbiosis) have been found to be associated with the development of psychosis. Earlylife stress, along with various stressors encountered in different developmental phases, have been shown to be associated with the abnormal composition of the gut microbiota, leading to irregular immunological and neuroendocrine functions, which are potentially responsible for the occurrence of firstepisode psychosis (FEP). The aim of the present narrative review was to summarize the significant differences of the altered microbiome composition in patients suffering from FEP vs. healthy controls, and to discuss its effects on the occurrence and intensity of symptoms in FEP.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos Psicóticos
/
Disbiose
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Microbioma Gastrointestinal
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article