Biomonitoring Study of Urinary Bisphenol A Levels and Impact of Bottle-Feeding Practices Among Infants and Children From Northern India.
Indian Pediatr
; 61(7): 649-655, 2024 Jul 15.
Article
em En
| MEDLINE
| ID: mdl-38803097
ABSTRACT
OBJECTIVES:
To compare the urinary bisphenol A (BPA) levels in bottle-fed and never bottle-fed infants and under-five children and to determine the impact of bottle-feeding practices and sociodemographic factors on urinary BPA levels.METHODS:
A community-based cross-sectional study was carried out on children aged between 2 to 60 months attending the Anganwadi centres in Chandigarh.RESULTS:
Urine samples were collected from 184 children, out of which 94.56% (n = 174) children had detectable urinary BPA levels. The mean (SD) BPA level was 2.74 (2.60) ng/ml and BPA was detected in 93.9% of 'ever' bottle-fed children (n = 93/99) and 95.3% of 'never' bottle-fed children (n = 81/85) (P = 0.69). On multivariate regression analysis, there were no significant predictors for high (≥ 75th percentile) urinary BPA levels. Still, the odds of urinary BPA levels ≥75th percentile showed higher trend for significance among children from middle/higher socioeconomic background in reference to lower socioeconomic stratum (adjusted OR 7.02; 95% CI 1.24, 133.25; P = 0.07) and among children whose feeding bottles were brushed once or twice daily in reference to group with no daily brushing (adjusted OR 3.92, 95% CI 0.95, 20.56; P = 0.07).CONCLUSIONS:
Although feeding with plastic bottle did not emerge as a statistically significant risk factor for BPA exposure, yet detection of BPA levels among majority of study children signals urgent need for unmasking exposure to other sources given the potential long-term toxicity of BPA among infants and young children.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fenóis
/
Compostos Benzidrílicos
/
Alimentação com Mamadeira
Limite:
Child, preschool
/
Female
/
Humans
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Infant
/
Male
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article