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DANMEL: A manually curated reference database for analyzing mobile genetic elements associated with bacterial drug resistance.
Wang, Peng; Jiang, Xiaoyuan; Mu, Kai; Jing, Ying; Yin, Zhe; Cui, Yujun; Li, Cuidan; Luo, Xinhua; Chen, Fangzhou; Yu, Ting; Zhu, Zhichen; Sun, Yansong; Chen, Fei; Zhou, Dongsheng.
Afiliação
  • Wang P; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Jiang X; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Mu K; Beijing Institute of Genomics, Chinese Academy of Sciences China National Center for Bioinformation Beijing China.
  • Jing Y; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Yin Z; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Cui Y; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Li C; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Luo X; Beijing Institute of Genomics, Chinese Academy of Sciences China National Center for Bioinformation Beijing China.
  • Chen F; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Yu T; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Zhu Z; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Sun Y; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Chen F; State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and Epidemiology Beijing China.
  • Zhou D; Beijing Institute of Genomics, Chinese Academy of Sciences China National Center for Bioinformation Beijing China.
mLife ; 1(4): 460-464, 2022 Dec.
Article em En | MEDLINE | ID: mdl-38818485
ABSTRACT
We have developed a manually curated online reference database, DANMEL (http//124.239.252.254/danmel/), that addresses the lack of accurate dissection and annotation of the genetic structures of mobile genetic elements (MGEs) with genes for drug resistance. DANMEL contains accurately annotated and genetically dissected reference MGEs covering 5 categories and 135 subcategories/subfamilies of MGEs. Further, DANMEL provides a detailed guide on how to precisely annotate MGEs. DANMEL also provides SEARCH/BLAST functions to facilitate finding reference MGEs. Overall, DANMEL will aid researchers to conduct in-depth genetic analysis of sequenced bacterial MGEs with drug-resistance genes and further facilitate a better understanding of bacterial MGEs associated with drug resistance at a genomic level.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article