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Comparison of postweaning bovine respiratory disease treatment rates between non-vaccinated control beef calves and calves variably primed and boosted using commercially available bovine coronavirus vaccines.
Erickson, Nathan E N; April, Sharlene; Campbell, John R; Homerosky, Elizabeth; Ware, Tommy; Dorin, Craig; Waldner, Cheryl L; Ellis, John A.
Afiliação
  • Erickson NEN; Department of Large Animal Clinical Sciences (Erickson, April, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Albe
  • April S; Department of Large Animal Clinical Sciences (Erickson, April, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Albe
  • Campbell JR; Department of Large Animal Clinical Sciences (Erickson, April, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Albe
  • Homerosky E; Department of Large Animal Clinical Sciences (Erickson, April, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Albe
  • Ware T; Department of Large Animal Clinical Sciences (Erickson, April, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Albe
  • Dorin C; Department of Large Animal Clinical Sciences (Erickson, April, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Albe
  • Waldner CL; Department of Large Animal Clinical Sciences (Erickson, April, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Albe
  • Ellis JA; Department of Large Animal Clinical Sciences (Erickson, April, Campbell, Waldner) and Department of Microbiology (Ellis), Western College of Veterinary Medicine, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4; Veterinary Agri-Health Services, 281121 Dickson Stevenson Trail, Rocky View County, Albe
Can Vet J ; 65(6): 581-586, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38827595
ABSTRACT

Objective:

Bovine respiratory disease (BRD) and overall postweaning treatment rates were compared among 3 groups of calves either differentially primed and boosted with commercially available bovine coronavirus (BCoV) vaccine or not vaccinated against BCoV. Animals Commercial heifer and steer beef calves born in April and May 2022. Procedure In June 2022, calves were randomly enrolled into 3 treatment groups. Those in 2 groups [V1 (n = 160) and V2 (n = 160)] were administered a mucosal priming dose of 1 of 2 commercial BCoV vaccines; those in the 3rd group [CTL (n = 151)] were unvaccinated against BCoV. The V1 and V2 groups were boosted by intramuscular injection pre-weaning with the same vaccine used for priming. Weaning occurred 3 wk after the last preweaning processing day. Ranch staff used a BRD case definition provided by their herd veterinarian to identify, treat, and record treatments for 45 d post-weaning.

Results:

Postweaning BRD treatment rates for V1, V2, and CTL were 7%, 9%, and 14%, respectively. The CTL calves had 2.2× greater odds of receiving treatment for BRD than V1 calves. There were no differences in odds of treatment between CTL and V2 calves or V1 and V2 calves.

Conclusion:

In a herd with previously diagnosed BCoV BRD cases, prime-boost vaccination of calves is associated with a difference in odds of BRD treatment post-weaning compared to not vaccinating calves against BCoV. Clinical relevance Prime-boost vaccination with commercial BCoV vaccine may be an important management tool for herds with known BCoV BRD outbreaks.
Comparaison des taux de traitement des maladies respiratoires bovines après le sevrage entre des veaux de boucherie témoins non vaccinés et des veaux vaccinés amorce-rappel de manière variable à l'aide de vaccins contre le coronavirus bovin commercialement disponibles. Objectif La maladie respiratoire bovine (BRD) et les taux globaux de traitement post-sevrage ont été comparés parmi 3 groupes de veaux soit vaccinés de manière différentielle et avec un rappel avec le vaccin contre le coronavirus bovin (BCoV) disponible commercialement, soit non vaccinés contre le BCoV. Animaux Génisses et veaux de boucherie commerciaux nés en avril et mai 2022. Procédure En juin 2022, les veaux ont été randomisés lors du recrutement dans 3 groupes de traitement. Ceux des 2 groupes [V1 (n = 160) et V2 (n = 160)] ont reçu une dose d'amorce par voie muqueuse de l'un des deux vaccins commerciaux BCoV; ceux du 3ème groupe [CTL (n = 151)] n'étaient pas vaccinés contre le BCoV. Les groupes V1 et V2 ont eu un rappel par injection intramusculaire avant le sevrage avec le même vaccin que celui utilisé pour l'amorçage. Le sevrage a eu lieu 3 semaines après le dernier jour de conditionnement pré-sevrage. Le personnel du ranch a utilisé une définition de cas de BRD fournie par le vétérinaire de leur troupeau pour identifier, traiter et enregistrer les traitements pendant 45 jours après le sevrage. Résultats Les taux de traitement BRD post-sevrage pour V1, V2 et CTL étaient respectivement de 7 %, 9 % et 14 %. Les veaux CTL avaient 2,2 fois plus de chances de recevoir un traitement contre la BRD que les veaux V1. Il n'y avait aucune différence dans les probabilités de traitement entre les veaux CTL et V2 ou entre les veaux V1 et V2.

Conclusion:

Dans un troupeau avec des cas de BRD causés par le BCoV déjà diagnostiqués, la vaccination amorce-rappel des veaux est associée à une différence de probabilité de traitement par le BRD après le sevrage par rapport à la nonvaccination des veaux contre le BCoV. Pertinence clinique La vaccination amorce-rappel avec le vaccin commercial BCoV peut être un outil de gestion important pour les troupeaux présentant des foyers connus de BCoV BRD.(Traduit par Dr Serge Messier).
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Virais / Coronavirus Bovino Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Virais / Coronavirus Bovino Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article