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Assessing motor development and function in mouse models of neurodevelopmental disorders.
Dierdorff, Lauren; Garcia-Forn, Marta; von Mueffling, Alexa; De Rubeis, Silvia.
Afiliação
  • Dierdorff L; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount
  • Garcia-Forn M; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount
  • von Mueffling A; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount
  • De Rubeis S; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount
Methods Cell Biol ; 188: 171-181, 2024.
Article em En | MEDLINE | ID: mdl-38880523
ABSTRACT
Alterations in motor development often accompany neurodevelopmental disorders (NDD) and can have an impact on social interaction and communication. Studying motor development and function in mouse models of NDDs can offer a window to identify underlying biological mechanisms and establish preclinical outcome measures for testing therapeutics. This chapter describes tests to measure motor developmental milestones early postnatally and adult motor functions in mouse models of NDDs.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Modelos Animais de Doenças / Transtornos do Neurodesenvolvimento Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Modelos Animais de Doenças / Transtornos do Neurodesenvolvimento Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article