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Nutritional Prehabilitation in Patients Undergoing Cystectomy: A Systematic Review.
Dal Bello, Susy; Mancin, Stefano; Morales Palomares, Sara; Lopane, Diego; Di Gianfrancesco, Luca; Soligo, Chiara; Tarantino, Tommaso; Perdonò, Paolo; Hurle, Rodolfo; Bernardini, Bruno; Piccioni, Federico; Pastore, Manuela; Pellegrinelli, Alvarez; Porreca, Angelo; Mazzoleni, Beatrice.
Afiliação
  • Dal Bello S; Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
  • Mancin S; IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
  • Morales Palomares S; Department of Pharmacy, Health and Nutritional Sciences (DFSSN), University of Calabria, 87036 Rende, Italy.
  • Lopane D; IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
  • Di Gianfrancesco L; Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
  • Soligo C; Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
  • Tarantino T; Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
  • Perdonò P; Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
  • Hurle R; IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
  • Bernardini B; IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
  • Piccioni F; IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
  • Pastore M; IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
  • Pellegrinelli A; Santa Chiara Hospital, 38122 Trento, Italy.
  • Porreca A; Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
  • Mazzoleni B; Department of Biomedical Sciences, Humanitas University, 20072 Milan, Italy.
Nutrients ; 16(11)2024 May 29.
Article em En | MEDLINE | ID: mdl-38892615
ABSTRACT
BACKGROUND/

AIM:

Nutrition is a key element of the prehabilitation process prior to surgery. The aim of this study was to identify the clinical pathways of nutritional prehabilitation before cystectomy.

METHODS:

A systematic literature review was conducted in PubMed, the Cochrane Library, CINAHL, Scopus and the Web of Science databases. Quality and risk of bias assessment was conducted adhering to the JBI framework and evidence was evaluated according to the Oxford Centre for Evidence Based Medicine levels of evidence.

RESULTS:

Out of 586 records identified, six studies were included. Among them, only two were randomized controlled trials. Immunonutrition has been shown to improve postoperative bowel function (3.12 vs. 3.74 days; RR 0.82; CI, 0.73-0.93; p = 0.0029) and decrease postoperative complications (-36.7%; p = 0.008) and readmission rates (-15.38%; p = 0.03). Furthermore, oral nutritional supplements combined with nutritional counseling demonstrated an accelerated recovery of bowel function (-1 day; p < 0.01), a reduction in the length of hospital stay (-1.75 days; p = 0.01), an improvement in handgrip strength (+6.8%, p < 0.001), an increase in bone mass (+0.3 kg, p = 0.04), and a better BMI value (+2.3%, p = 0.001).

CONCLUSIONS:

Nutritional prehabilitation demonstrates potential in enhancing postoperative outcomes following radical cystectomy. Oral supplements, immunonutrition, and counseling exhibit efficacy in improving postoperative results.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Cistectomia Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Cistectomia Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article