Copper-Catalyzed Three-Component Synthesis of ß-Hydroxysulfides from Styrene Oxide, Aryl Iodide, and Carbon Disulfide.
J Org Chem
; 89(13): 9287-9297, 2024 Jul 05.
Article
em En
| MEDLINE
| ID: mdl-38896800
ABSTRACT
A copper-catalyzed three-component coupling reaction of styrene oxide, aryl iodide, and carbon disulfide for the construction of ß-hydroxysulfides has been developed. In this process, readily available CS2 was used as the sulfur source to construct C-S bonds for the synthesis of phenyl-ß-hydroxysulfides and (benzo[d]thiazol)-ß-hydroxysulfides. This process features mild reaction conditions, simple operation, and wide substrate scope (>50 examples).
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Coleções:
01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article