Gastroretentive fibrous dosage forms for prolonged delivery of sparingly-soluble tyrosine kinase inhibitors. Part 1: Dosage form design, and models of expansion, post-expansion mechanical strength, and drug release.

Blaesi, Aron H; Saka, Nannaji

Blaesi, Aron H; Saka, Nannaji.

Afiliação

Blaesi AH; Enzian Pharmaceutics Blaesi AG, CH-7078 Lenzerheide, Switzerland; Enzian Pharmaceutics, Inc., Cambridge, MA 02139, USA. Electronic address: ablaesi@enzianpharma.com.
Saka N; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Int J Pharm ; : 124360, 2024 Jun 21.

Article em En | MEDLINE | ID: mdl-38909925

Palavras-chave

3D-printed dosage forms; Controlled drug delivery; Drug concentration in blood; Fibrous dosage forms; Gastroretentive dosage forms; Prolonged drug delivery; Tyrosine kinase inhibitors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article