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Late-Season Influenza Vaccine Effectiveness Against Medically Attended Outpatient Illness, United States, December 2022-April 2023.
Chung, Jessie R; Shirk, Philip; Gaglani, Manjusha; Mutnal, Manohar B; Nowalk, Mary Patricia; Moehling Geffel, Krissy; House, Stacey L; Curley, Tara; Wernli, Karen J; Kiniry, Erika L; Martin, Emily T; Vaughn, Ivana A; Murugan, Vel; Lim, Efrem S; Saade, Elie; Faryar, Kiran; Williams, Olivia L; Walter, Emmanuel B; Price, Ashley M; Barnes, John R; DaSilva, Juliana; Kondor, Rebecca; Ellington, Sascha; Flannery, Brendan.
Afiliação
  • Chung JR; Influenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Shirk P; Influenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Gaglani M; Baylor Scott & White Health, Temple, Texas, USA.
  • Mutnal MB; Department of Pediatrics, Baylor College of Medicine, Temple, Texas, USA.
  • Nowalk MP; Baylor Scott & White Health, Temple, Texas, USA.
  • Moehling Geffel K; Department of Pediatrics, Baylor College of Medicine, Temple, Texas, USA.
  • House SL; Department of Family Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Curley T; Department of Family Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Wernli KJ; Department of Emergency Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
  • Kiniry EL; Department of Emergency Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
  • Martin ET; Kaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
  • Vaughn IA; Department of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California, USA.
  • Murugan V; Kaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
  • Lim ES; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
  • Saade E; Henry Ford Health, Detroit, Michigan, USA.
  • Faryar K; Biodesign Center for Personalized Diagnostics, Arizona State University, Tempe, Arizona, USA.
  • Williams OL; Biodesign Center for Fundamental & Applied Microbiomics, Arizona State University, Tempe, Arizona, USA.
  • Walter EB; Division of Infectious Diseases and HIV Medicine, University Hospitals of Cleveland, Cleveland, Ohio, USA.
  • Price AM; Department of Emergency Medicine, University Hospitals of Cleveland, Cleveland, Ohio, USA.
  • Barnes JR; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • DaSilva J; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.
  • Kondor R; Influenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Ellington S; Influenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Flannery B; Influenza Division, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Influenza Other Respir Viruses ; 18(6): e13342, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38923314
ABSTRACT

BACKGROUND:

The 2022-23 US influenza season peaked early in fall 2022.

METHODS:

Late-season influenza vaccine effectiveness (VE) against outpatient, laboratory-confirmed influenza was calculated among participants of the US Influenza VE Network using a test-negative design.

RESULTS:

Of 2561 participants enrolled from December 12, 2022 to April 30, 2023, 91 laboratory-confirmed influenza cases primarily had A(H1N1)pdm09 (6B.1A.5a.2a.1) or A(H3N2) (3C.2a1b.2a.2b). Overall, VE was 30% (95% confidence interval -9%, 54%); low late-season activity precluded estimation for most subgroups.

CONCLUSIONS:

2022-23 late-season outpatient influenza VE was not statistically significant. Genomic characterization may improve the identification of influenza viruses that circulate postinfluenza peak.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pacientes Ambulatoriais / Estações do Ano / Vacinas contra Influenza / Influenza Humana / Vírus da Influenza A Subtipo H1N1 / Vírus da Influenza A Subtipo H3N2 / Eficácia de Vacinas Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: America do norte Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pacientes Ambulatoriais / Estações do Ano / Vacinas contra Influenza / Influenza Humana / Vírus da Influenza A Subtipo H1N1 / Vírus da Influenza A Subtipo H3N2 / Eficácia de Vacinas Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: America do norte Idioma: En Ano de publicação: 2024 Tipo de documento: Article