Facile Preparation of Tough, Puncture-Resistant Antibacterial Polyrotaxane Hydrogel.
ACS Appl Mater Interfaces
; 16(28): 37041-37051, 2024 Jul 17.
Article
em En
| MEDLINE
| ID: mdl-38950151
ABSTRACT
Slide-ring hydrogels containing polyrotaxane structures have been widely developed, but current methods are more complex, in which modified cyclodextrins, capped polyrotaxanes, and multistep reactions are often needed. Here, a simple one-pot method dissolving the pseudopolyrotaxane (pPRX) in a mixture of acrylamide and boric acid to form a slide-ring hydrogel by UV light is used to construct a tough, puncture-resistant antibacterial polyrotaxane hydrogel. As a new dynamic ring cross-linking agent, boric acid effectively improves the mechanical properties of the hydrogel and involves the hydrogel with fracture toughness. The polyrotaxane hydrogel can withstand 1 MPa compression stress and maintain the morphology integrity, showing 197.5 mJ puncture energy under a sharp steel needle puncture. Meanwhile, its significant antibacterial properties endow the hydrogel with potential applications in the biomedical field.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poloxâmero
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Hidrogéis
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Ciclodextrinas
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Rotaxanos
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Escherichia coli
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Antibacterianos
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article