Using absorbance detection for hs-SV-AUC characterization of adeno-associated virus.
Anal Biochem
; 694: 115617, 2024 Nov.
Article
em En
| MEDLINE
| ID: mdl-39019206
ABSTRACT
Data are presented demonstrating that absorbance detection can be used during high-speed sedimentation velocity analytical ultracentrifugation (hs-SV-AUC) experiments to characterize the size distribution of adeno-associated virus (AAV) drug products accurately. Advantages and limitations of being able to use this detector in this specific type of SV-AUC experiment are discussed.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ultracentrifugação
/
Dependovirus
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article