Prevalence and prognostic role of thoracic lymphadenopathy in Covid-19. / Prävalenz und prognostische Rolle der thorakalen Lymphadenopathie bei Covid-19.
Rofo
; 2024 Jul 22.
Article
em En, De
| MEDLINE
| ID: mdl-39038457
ABSTRACT
PURPOSE:
The prevalent coronavirus disease 2019 (COVID-19) pandemic has spread throughout the world and is considered a serious threat to global health. The prognostic role of thoracic lymphadenopathy in COVID-19 is unclear. The aim of the present meta-analysis was to analyze the prognostic role of thoracic lymphadenopathy for the prediction of 30-day mortality in patients with COVID-19. MATERIALS ANDMETHODS:
The MEDLINE library, Cochrane, and SCOPUS databases were screened for associations between CT-defined features and mortality in COVID-19 patients up to June 2021. In total, 21 studies were included in the present analysis. The quality of the included studies was assessed by the Newcastle-Ottawa Scale. The meta-analysis was performed using RevMan 5.3. Heterogeneity was calculated by means of the inconsistency index I2. DerSimonian and Laird random-effect models with inverse variance weights were performed without any further correction.RESULTS:
The included studies comprised 4621 patients. The prevalence of thoracic lymphadenopathy varied between 1â% and 73.4â%. The pooled prevalence was 16.7â%, 95â% CIâ=â(15.6â%; 17.8â%). The hospital mortality was higher in patients with thoracic lymphadenopathy (34.7â%) than in patients without (20.0â%). The pooled odds ratio for the influence of thoracic lymphadenopathy on mortality was 2.13 (95â% CIâ=â[1.80-2.52], pâ<â0.001).CONCLUSION:
The prevalence of thoracic lymphadenopathy in COVID-19 is 16.7â%. The presence of thoracic lymphadenopathy is associated with an approximately twofold increase in the risk for hospital mortality in COVID-19. KEY POINTS · The prevalence of lymphadenopathy in COVID-19 is 16.7â%.. · Patients with lymphadenopathy in COVID-19 have a higher risk of mortality during hospitalization.. · Lymphadenopathy nearly doubles mortality and plays an important prognostic role.. CITATION FORMAT · Bucher AM, Sieren M, Meinel F etâal. Prevalence and prognostic role of thoracic lymphadenopathy in Covid-19. Fortschr Röntgenstr 2024; DOI 10.1055/a-2293-8132.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
De
/
En
Ano de publicação:
2024
Tipo de documento:
Article