Significant pituitary siderosis is common in transfusion-dependent sickle cell disease.
Blood
; 144(13): 1457-1459, 2024 Sep 26.
Article
em En
| MEDLINE
| ID: mdl-39046820
ABSTRACT
ABSTRACT Chronically transfused patients with sickle cell disease typically do not exhibit iron-mediated extrahepatic toxicity. However, we demonstrate that the pituitary gland is vulnerable to iron deposition, and it occurs regardless of other extrahepatic involvement. Severe pituitary siderosis is associated with early organ dysfunction.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Siderose
/
Anemia Falciforme
Limite:
Adolescent
/
Adult
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Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article