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Emergence and properties of adult mammalian epidermal stem cells.
Gadre, Purna; Markova, Pavlina; Ebrahimkutty, Mirsana; Jiang, Yidan; Bouzada, Francisco M; Watt, Fiona M.
Afiliação
  • Gadre P; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany.
  • Markova P; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany.
  • Ebrahimkutty M; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany.
  • Jiang Y; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany.
  • Bouzada FM; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany.
  • Watt FM; Directors' Unit, EMBL-Heidelberg, Meyerhofstr. 1, 69117, Heidelberg, Germany. Electronic address: Fiona.watt@embo.org.
Dev Biol ; 515: 129-138, 2024 Nov.
Article em En | MEDLINE | ID: mdl-39059680
ABSTRACT
In this review we discuss how the mammalian interfollicular epidermis forms during development, maintains homeostasis, and is repaired following wounding. Recent studies have provided new insights into the relationship between the stem cell compartment and the differentiating cell layers; the ability of differentiated cells to dedifferentiate into stem cells; and the epigenetic memory of epidermal cells following wounding.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Epiderme / Células-Tronco Adultas / Células Epidérmicas Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Epiderme / Células-Tronco Adultas / Células Epidérmicas Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article