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Effects of Probiotic Supplementation Added to a Weight Loss Program on Anthropometric Measures, Body Composition, Eating Behavior, and Related Hormone Levels in Patients with Food Addiction and Weight Regain After Bariatric Surgery: A Randomized Clinical Trial.
Ghafouri-Taleghani, Fateme; Tafreshi, Asa Sarabadani; Doost, Azita Hekmat; Tabesh, Mastaneh; Abolhasani, Maryam; Amini, Amin; Saidpour, Atoosa.
Afiliação
  • Ghafouri-Taleghani F; Department of Clinical Nutrition & Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, 1981619573, Iran.
  • Tafreshi AS; Department of Clinical Psychology, Qazvin Islamic Azad University, Qazvin, 3471993116, Iran.
  • Doost AH; Department of Clinical Nutrition & Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, 1981619573, Iran.
  • Tabesh M; Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Center, Tehran University of Medical Sciences, Tehran, 1136746911, Iran.
  • Abolhasani M; Cardiac Primary Prevention Research Center, Cardiovascular Diseases Research Center, Tehran University of Medical Sciences, Tehran, 1136746911, Iran.
  • Amini A; Department of Biostatistics, Faculty of Paramedical, Shahid Beheshti University of Medical Sciences, Tehran, 1971653313, Iran.
  • Saidpour A; Department of Clinical Nutrition & Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, 1981619573, Iran. atoosa.saidpour@gmail.com.
Obes Surg ; 34(9): 3181-3194, 2024 Sep.
Article em En | MEDLINE | ID: mdl-39117856
ABSTRACT

PURPOSE:

Weight regain after metabolic bariatric surgery is a common problem. Food addiction is an eating disorder that can be one of the reasons for weight regain in these patients. This study aimed to evaluate the effects of probiotic supplementation with a weight loss program and cognitive behavioral therapy (CBT) on anthropometric measures, eating behavior, food addiction, and related hormone levels, in patients with food addiction and weight regain after metabolic bariatric surgery. MATERIALS AND

METHODS:

This randomized, triple-blind, placebo-controlled clinical trial was conducted on patients with food addiction and weight regain after metabolic bariatric surgery. Participants (n = 50) received a weight loss program and CBT plus probiotic, or placebo for 12 weeks. Then, anthropometric measurements, biochemical markers, eating behavior, and food addiction were assessed.

RESULTS:

Weight and body mass index (BMI) decreased significantly in the probiotic group compared to placebo (p = 0.008, p = 0.001, respectively). Fat mass was significantly decreased in the probiotic group (p < 0.001). Moreover, a significant improvement was observed in the probiotic group's eating behavior and food addiction compared to the placebo group (p < 0.001). Serum levels of leptin decreased significantly (p = 0.02), and oxytocin serum levels increased significantly (p = 0.008) in the probiotic group compared to the placebo group.

CONCLUSION:

Adding probiotic supplements to the weight loss program and CBT is superior to the weight loss program and CBT alone in improving weight loss, eating behavior, and food addiction in patients with food addiction and weight regain after metabolic bariatric surgery.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Composição Corporal / Obesidade Mórbida / Aumento de Peso / Terapia Cognitivo-Comportamental / Probióticos / Cirurgia Bariátrica / Comportamento Alimentar / Dependência de Alimentos Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Composição Corporal / Obesidade Mórbida / Aumento de Peso / Terapia Cognitivo-Comportamental / Probióticos / Cirurgia Bariátrica / Comportamento Alimentar / Dependência de Alimentos Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article