Your browser doesn't support javascript.
loading
Virulence of banana wilt-causing fungal pathogen Fusarium oxysporum tropical race 4 is mediated by nitric oxide biosynthesis and accessory genes.
Zhang, Yong; Liu, Siwen; Mostert, Diane; Yu, Houlin; Zhuo, Mengxia; Li, Gengtan; Zuo, Cunwu; Haridas, Sajeet; Webster, Katie; Li, Minhui; Grigoriev, Igor V; Yi, Ganjun; Viljoen, Altus; Li, Chunyu; Ma, Li-Jun.
Afiliação
  • Zhang Y; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, MA, USA.
  • Liu S; NIH-National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
  • Mostert D; Key Laboratory of South Subtropical Fruit Biology and Genetic Resource Utilization, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Science and Technology Research on Fruit Tree; Institute of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou
  • Yu H; Guangdong Laboratory for Lingnan Modern Agriculture of Maoming sub-center, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
  • Zhuo M; Department of Plant Pathology, Stellenbosch University, Stellenbosch, South Africa.
  • Li G; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, MA, USA.
  • Zuo C; Plant Biology, University of Massachusetts Amherst, Amherst, MA, USA.
  • Haridas S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Webster K; Key Laboratory of South Subtropical Fruit Biology and Genetic Resource Utilization, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Science and Technology Research on Fruit Tree; Institute of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou
  • Li M; Guangdong Laboratory for Lingnan Modern Agriculture of Maoming sub-center, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
  • Grigoriev IV; Department of Biochemistry and Molecular Biology, University of Massachusetts Amherst, Amherst, MA, USA.
  • Yi G; Key Laboratory of South Subtropical Fruit Biology and Genetic Resource Utilization, Ministry of Agriculture and Rural Affairs; Guangdong Provincial Key Laboratory of Science and Technology Research on Fruit Tree; Institute of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou
  • Viljoen A; US Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
  • Li C; Plant Biology, University of Massachusetts Amherst, Amherst, MA, USA.
  • Ma LJ; Department of Plant Pathology/Guangdong Province Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University, Guangzhou, China.
Nat Microbiol ; 9(9): 2232-2243, 2024 Sep.
Article em En | MEDLINE | ID: mdl-39152292
ABSTRACT
Fusarium wilt of banana, caused by Fusarium oxysporum f. sp. cubense (Foc), is one of the most damaging plant diseases known. Foc race 1 (R1) decimated the Gros Michel-based banana (Musa acuminata) trade, and now Foc tropical race 4 (TR4) threatens global production of its replacement, the Cavendish banana. Here population genomics revealed that all Cavendish banana-infecting Foc race 4 strains share an evolutionary origin distinct from that of R1 strains. Although TR4 lacks accessory chromosomes, it contains accessory genes at the ends of some core chromosomes that are enriched for virulence and mitochondria-related functions. Meta-transcriptomics revealed the unique induction of the entire mitochondrion-localized nitric oxide (NO) biosynthesis pathway upon TR4 infection. Empirically, we confirmed the unique induction of a NO burst in TR4, suggesting that nitrosative pressure may contribute to virulence. Targeted mutagenesis demonstrated the functional importance of fungal NO production and the accessory gene SIX4 as virulence factors.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças das Plantas / Musa / Fusarium / Óxido Nítrico Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças das Plantas / Musa / Fusarium / Óxido Nítrico Idioma: En Ano de publicação: 2024 Tipo de documento: Article