Dual-Enhancement Electrochemiluminescence Device for Ultratrace Uranium Visualized Monitoring in Fish, Hair, and Nail Samples.
Anal Chem
; 96(36): 14604-14611, 2024 Sep 10.
Article
em En
| MEDLINE
| ID: mdl-39190775
ABSTRACT
Uranium is a nuclear fuel but also a hazardous contaminant due to its radioactivity and chemical toxicity. To prevent and mitigate its potential threat, the accurate monitoring of ultratrace uranium (orders of magnitude of pg g-1) in practical environmental samples has become an important scientific problem. To meet this challenge, we developed an efficient electrochemiluminescence (ECL) UO22+ detection device by a novel dual-enhancement mechanism. In detail, poly[(9,9-dioctylfuor-enyl-2,7-diyl)-alt-co-(1,4-benzo-{2,1,3}-thiadiazole)] polymer dots (Pdots) are modified by the UO22+ DNA aptamer, and rhodamine B (RhB) is combined with dsDNA to quench the ECL signal via a resonance energy transfer (RET) process. UO22+ can cut off the DNA aptamer to release RhB, which generates an ECL enhancement process, and then, UO22+ continuously combines with the DNA chain, inducing another ECL enhancement by the RET process from UO22+ to Pdots. This device achieves an ultralow detection limit (12 pg L-1) and a wide linear range (113 pg L-1-11.3 mg L-1), which can successfully give accurate determination results to the ultratrace uranium in biosamples (<1 pg g-1) to monitor the uranium simulation of fish. This work presents an efficient strategy for ultratrace uranium determination in the environment, highlighting its significance in public health and environmental fields.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Urânio
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Técnicas Eletroquímicas
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Peixes
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Medições Luminescentes
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article