Your browser doesn't support javascript.
loading
Toddler disorganized attachment in relation to cortical thickness and socioemotional problems in late childhood.
Arya, Bhavya; Patrick, Madeline; Pei, Huang; Law, Evelyn; Broekman, Birit; Chen, Helen; Chan Hiu Gwan, Madeline; Yap, Fabian; Yung Seng, Lee; Tan, Kok Hian; Yap-Seng, Chong; Qiu, Anqi; Fortier, Marielle Valerie; Gluckman, Peter; Meaney, Michael; Tan, Ai Peng; Rifkin-Graboi, Anne.
Afiliação
  • Arya B; Department of Psychology, School of Social Sciences, Nanyang Technological University, Singapore.
  • Patrick M; Department of Psychological Sciences, University of Missouri, Columbia, USA.
  • Pei H; Translational Neuroscience, Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Republic of Singapore.
  • Law E; Translational Neuroscience, Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Republic of Singapore.
  • Broekman B; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Chen H; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.
  • Chan Hiu Gwan M; Department of Psychiatry and Psychological Medicine, Amsterdam Public Health, Amsterdam, the Netherlands.
  • Yap F; Department of Psychological Medicine, KK Women's and Children's Hospital.
  • Yung Seng L; Duke-NUS Medical School, Singapore, Singapore.
  • Tan KH; Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore.
  • Yap-Seng C; Endocrinology Service, Division of Medicine, KK Women's and Children's Hospital, Singapore.
  • Qiu A; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Fortier MV; Duke-NUS Medical School, Singapore, Singapore.
  • Gluckman P; Department of Maternal-Fetal Medicine, KK Women's and Children's Hospital, Singapore, Singapore.
  • Meaney M; Singapore Institute for Clinical Science, Agency for Science, Technology and Research, Singapore, Singapore.
  • Tan AP; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore.
  • Rifkin-Graboi A; Department of Biomedical Engineering, National University of Singapore, Singapore.
Attach Hum Dev ; : 1-21, 2024 Sep 24.
Article em En | MEDLINE | ID: mdl-39316717
ABSTRACT
Disorganized attachment is a risk for mental health problems, with increasing work focused on understanding biological mechanisms. Examining late childhood brain morphology may be informative - this stage coincides with the onset of many mental health problems. Past late childhood research reveals promising candidates, including frontal lobe cortical thickness and hippocampal volume. However, work has been limited to Western samples and has not investigated mediation or moderation by brain morphology. Furthermore, past cortical thickness research included only 33 participants. The current study utilized data from 166 children from the GUSTO Asian cohort, who participated in strange situations at 18 months and MRI brain imaging at 10.5 years, with 124 administered the Child Behaviour Checklist at 10.5 years. Results demonstrated disorganization liked to internalizing problems, but no mediation or moderation by brain morphology. The association to internalizing (but not externalizing) problems is discussed with reference to the comparatively higher prevalence of internalizing problems in Singapore.
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article