Cytogenetic study in six Spanish patients with Burkitt's lymphoma.
Cancer Genet Cytogenet
; 14(3-4): 339-46, 1985 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-3967210
ABSTRACT
A cytogenetic study carried out on affected tissues of six children with Burkitt's lymphoma revealed five cases with a typical translocation (8q-; 14q+) and one with a variant t(2p-; 8q+). Additional cytogenetic variations were present in three cases. One had two acrocentric marker chromosomes comprised of material from chromosome #1 (1q21----q44) translocated to the Y gonosome. The other two cases had a cytogenetic alteration of chromosome #12. Cytogenetic studies carried out systematically in Burkitt's lymphoma could be a great help in possibly establishing differences in the biologic and clinical aspects of cases presenting with the t(8;14) versus cases with variant translocations, as this would allow for classification of these patients into groups which, at present, cannot be differentiated using other diagnostic methods.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
/
Cromossomos Humanos 13-15
/
Cromossomos Humanos 6-12 e X
/
Linfoma de Burkitt
Limite:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Male
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article