[Myocardial myoglobin in some types of cardiac pathology in the far northeastern USSR]. / Mioglobin miokarda pri nekotorykh vidakh patologii serdtsa na Krainem Severo-Vostoka SSSR.

Immunomorphological and biochemical study of the myoglobin in the myocardium of 118 males at the age of from 30 to 55 years who died suddenly from coronary insufficiency, chronic pulmonary-cardiac insufficiency and from alcoholic cardiomyopathy in Magadan and Moscow is described. A decrease of the myoglobin concentration is revealed in the myocardium of the practically healthy Magadan citizeus as compared to that of moscovites. When the death occurred suddenly reduction of the myoglobin content is noted in the left ventricle simultaneously with its hypertrophy. It is shown immunomorphologically that myoglobin in the cytoplasm of cardiomyocytes is observed in the form of dense foci, granules and streaks. The myoglobin concentration tend to the reduction when there was hypertrophy of the right ventricle in patients dying from chronic pulmonary-cardiac insufficiency. Almost two-fold decrease of the myoglobin concentration in the left ventricle without its visible hypertrophy was observed in alcoholic cardiomyopathy, this may serve as a complementary test in the diagnosis of this disease.