Maintenance of skin xenografts of widely divergent phylogenetic origin of congenitally athymic (nude) mice.
J Exp Med
; 138(2): 488-94, 1973 Aug 01.
Article
em En
| MEDLINE
| ID: mdl-4578300
ABSTRACT
Congenitally athymic (nude) mice accepted for their lifetime intact skin grafts from distantly related mammals (cat, human) and birds (chicken). They also failed to immunologically reject skin grafts from reptiles (lizards) and amphibians (tree frog), although the skin in these grafts underwent varying degrees of disorganization. A definitive role for the thymic defect in this failure to reject xenografts was established by showing that thymus implantation into nude mice enabled them to reject such foreign skin.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante Heterólogo
/
Transplante de Pele
/
Rejeição de Enxerto
Limite:
Animals
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Female
/
Humans
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Male
Idioma:
En
Ano de publicação:
1973
Tipo de documento:
Article