Lipid packing and transbilayer asymmetries of mixed lipid vesicles.
Biochim Biophys Acta
; 554(2): 340-57, 1979 Jul 05.
Article
em En
| MEDLINE
| ID: mdl-486446
ABSTRACT
Predictions, based on a previously developed theory, of the radii and asymmetric lipid distribution of mixed phosphatidylcholine/lysophosphatidylcholine and phosphatidylcholine/cholesterol vesicles of variable composition are presented. The results compare well with available experimental data, except for cis-unsaturated phosphatidylcholine/cholesterol vesicles at high concentrations of cholesterol. It is concluded that specific lipid-lipid interactions need not be invoked for saturated and trans-unsaturated phosphatidylcholine mixed with lysophosphatidylcholine or cholesterol. A discussion of the effect of packing stresses on induced flip-flop and non-spherical vesicles is also presented.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosfatidilcolinas
/
Lisofosfatidilcolinas
/
Colesterol
/
Bicamadas Lipídicas
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
1979
Tipo de documento:
Article