The effects of ions on the binding of agonists and antagonists to muscarinic receptors.
Br J Pharmacol
; 67(3): 371-7, 1979 Nov.
Article
em En
| MEDLINE
| ID: mdl-497538
ABSTRACT
1 There are no selective effects of Na+, K+, Ca2+, Mg2+ or Cl- on the binding of antagonists or agonists to muscarinic receptors in rat brain. A decrease in affinity related to ionic strength is found for all these ions. 2 Larger effects were produced by T1+, La3+, and some transition metal ions.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Parassimpatolíticos
/
Parassimpatomiméticos
/
Receptores Colinérgicos
/
Receptores Muscarínicos
/
Íons
Limite:
Animals
Idioma:
En
Ano de publicação:
1979
Tipo de documento:
Article