Oral (or nasogastric) maintenance therapy for cholera patients in all age-groups.
Bull World Health Organ
; 43(3): 361-3, 1970.
Article
em En
| MEDLINE
| ID: mdl-5312989
PIP: 56 children and 50 adults were studied to determine the effectiveness of an oral (or nasogastric) therapy with a glucose-electrolyte solution for treating cholera patients. The development of this inexpensive regimen is described. The therapy has the advantages of being cheap, not requiring sterile conditions, and having wide availability in endemic areas. The oral solution contained the following ions (as milliequivalents per liter of water): Na+, 120 K+, 25; CO2-, 48; CL-, 97; and glucose at 110 mmol/liter. Patients received nothing orally except the solution and a 5-day course of tetracycline (dosed according to body weight). The oral (or nasogastric) therapy was used as a supplement when patients arrived in shock, at which time intravenous infusion was used to begin rehydration; patients with milder cholera cases were given only the oral therapy, with much success. All children were maintained in a positive balance with the oral (or nasogastric) solution after correction of shock by intravenous rehydration, and the mean volume of oral solution required by the 56 children was 6 liters. In field trials, 80% of the patients were in positive net intestinal balance by 6 hours after initiation of oral therapy. Adults studied to determine in the 25 mEq potassium/liter solution was safe showed that after administration adult plasma potassium levels were normal.^ieng
Palavras-chave
Age Factors; Biology; Cardiovascular Effects; Demographic Factors; Diarrhea; Diarrhea, Infantile; Diseases; Electrolyte Balance; Hematological Effects; Hemic System; Homeostasis; Oral Rehydration; Physiology; Population; Population Characteristics; Potassium Ion Level; Prospective Studies; Research Methodology; Studies; Treatment
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bicarbonatos
/
Cloreto de Sódio
/
Cólera
/
Glucose
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Child
/
Child, preschool
/
Humans
Idioma:
En
Ano de publicação:
1970
Tipo de documento:
Article