Induction of differentiation in Herpetomonas samuelpessoai by dimethylsulfoxide.
Acta Trop
; 38(1): 29-37, 1981 Mar.
Article
em En
| MEDLINE
| ID: mdl-6111914
ABSTRACT
Dimethylsulfoxide (DMSO) induces in Herpetomonas samuelpessoai, grown in a chemically defined medium at 28 degrees C the transformation of promastigotes into paramastigotes and opisthomastigotes. This effect was dependent on the period of cultivation and the concentration of DMSO. Initially, DMSO induced the appearance of paramastigotes and later, of opisthomastigotes. Approximately 43% opisthomastigotes were obtained after growth of the protozoan for 96 h at 28 degrees C in a medium containing 3% DMSO. No ultrastructural changes were observed on DMSO-treated cells. Based on these results and others previously described, the process of differentiation in Herpetomonas is compared and analyzed with that occurring in Trypanosoma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dimetil Sulfóxido
/
Eucariotos
Limite:
Animals
Idioma:
En
Ano de publicação:
1981
Tipo de documento:
Article