Chromosomal location of a human alpha interferon gene family.

Slate, D L; D'Eustachio, P; Pravtcheva, D; Cunningham, A C; Nagata, S; Weissmann, C; Ruddle, F H

Slate, D L; D'Eustachio, P; Pravtcheva, D; Cunningham, A C; Nagata, S; Weissmann, C; Ruddle, F H.

J Exp Med ; 155(4): 1019-24, 1982 Apr 01.

Article em En | MEDLINE | ID: mdl-6174667

ABSTRACT

ABSTRACT

To determine the chromosomal location of the human alpha interferon genes, we scored a series of human/rodent somatic cell hybrids for the presence of DNA sequences hybridizing to an alpha 1 interferon DNA probe. The presence of human chromosome 9 in a hybrid correlated with the presence of a family of alpha interferon genes.

Assuntos

Mapeamento Cromossômico; Interferons/genética; Animais; Cromossomos Humanos 6-12 e X; Cricetinae; Cricetulus; DNA/genética; Humanos; Hibridização Genética; Camundongos; Camundongos Endogâmicos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mapeamento Cromossômico / Interferons Limite: Animals / Humans Idioma: En Ano de publicação: 1982 Tipo de documento: Article

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