Lymphocyte studies in a patient with chronic polyradiculoneuropathy.
Neurology
; 32(10): 1127-32, 1982 Oct.
Article
em En
| MEDLINE
| ID: mdl-6214729
ABSTRACT
We studied immunologic abnormalities in one patient with chronic polyradiculoneuropathy and the effects of immune suppression and plasmapheresis on the clinical course and immune abnormalities. Increased helper T cells and B cells with deficiency of T suppressor cells to B-cell but not to T-cell targets were detected. The patient's blood lymphocytes, but not the controls' lymphocytes, proliferated in vitro on culturing them with P2 antigen in the presence of the patient's CSF. Plasmapheresis combined with corticosteroid and azathioprine reversed the majority of immune abnormalities to normal but did not decrease the patient's lymphocyte-P2 proliferative response; nor did it improve clinical status.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polirradiculoneuropatia
/
Linfócitos
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1982
Tipo de documento:
Article