Electrolytically labeled [99mTc]MDP: chromatographic pattern, stability and biodistribution in rats.
Int J Appl Radiat Isot
; 35(8): 709-13, 1984 Aug.
Article
em En
| MEDLINE
| ID: mdl-6237064
ABSTRACT
The labeling of methylene diphosphonate with 99mTc is possible after reduction of pertechnetate by means of controlled potential electrolysis. This results in a [99mTc]MDP complex which differs slightly from 99mTc(Sn)-MDP in paper and gel chromatography. The scintigraphic images of both preparations are comparable in quality. Biodistribution in rats shows a higher bone uptake for the 99mTc(Sn)-MDP complex, whereas [99mTc]MDP shows a higher uptake in the gastric wall.
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01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tecnécio
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Difosfonatos
Limite:
Animals
Idioma:
En
Ano de publicação:
1984
Tipo de documento:
Article