Comparison of Tc-99m pyrosphosphate and Tc-99m hydroxymethylene diphosphonate in acute myocardial infarction: concise communication.
J Nucl Med
; 21(3): 203-6, 1980 Mar.
Article
em En
| MEDLINE
| ID: mdl-6245193
ABSTRACT
A clinical comparison between a new bone seeking radiopharmaceutical, Tc-99m hydroxymethylene diphosphonate (TcHMDP) and the standard agent, Tc-99m pyrophosphate (TcPPi), was performed in 18 patients with acute myocardial infarction. Each patient was imaged initially with either TcHMDP or TcPPi, and imaged 24 hr later with the other tracer. All 18 patients had images positive for acute myocardial infarction with TcPPi, whereas 16 of 18 patients (89%) had positive studies with TcHMDP. The TcPPi images were graded significantly superior to those obtained with TcHMDP in 61% of the patients, and they were equal in 33%. In only one patient (6%) was TcHMDP better. The results indicate that compared with TcHMDP, TcPPi not only has a superior sensitivity for acute myocardial infarction but also has a significantly increased intensity of uptake in positive areas. TcPPi remains the agent of choice for myocardial infarct imaging.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Medronato de Tecnécio Tc 99m
/
Tecnécio
/
Difosfatos
/
Difosfonatos
/
Coração
/
Infarto do Miocárdio
Tipo de estudo:
Observational_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
1980
Tipo de documento:
Article