Intranuclear distribution of herpes simplex virus type 2 DNA synthesis: examination by light and electron microscopy.
J Gen Virol
; 64 (Pt 9): 2087-92, 1983 Sep.
Article
em En
| MEDLINE
| ID: mdl-6310045
ABSTRACT
Uptake of [3H]thymidine by serum-starved baby hamster kidney cells infected with herpes simplex virus type 2 was investigated by light microscopic and electron microscopic autoradiography. The distribution of incorporated label altered throughout the period of viral DNA synthesis. It was restricted initially to a few well-defined sites within the nucleus which increased in size and spread as infection proceeded until the entire nucleus was involved. The label was not associated with any identifiable subnuclear structure although there was a high degree of association with the nuclear membrane at early times post-infection.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA Viral
/
Núcleo Celular
/
Simplexvirus
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
1983
Tipo de documento:
Article