Acetylcholine receptor: an allosteric protein.
Science
; 225(4668): 1335-45, 1984 Sep 21.
Article
em En
| MEDLINE
| ID: mdl-6382611
ABSTRACT
The nicotine receptor for the neurotransmitter acetylcholine is an allosteric protein composed of four different subunits assembled in a transmembrane pentamer alpha 2 beta gamma delta. The protein carries two acetylcholine sites at the level of the alpha subunits and contains the ion channel. The complete sequence of the four subunits is known. The membrane-bound protein undergoes conformational transitions that regulate the opening of the ion channel and are affected by various categories of pharmacologically active ligands.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores Nicotínicos
Limite:
Animals
Idioma:
En
Ano de publicação:
1984
Tipo de documento:
Article