[The use of prostaglandins to perform terminations of pregnancy in the second trimester (author's transl)]. / Utilisation des prostaglandines pour les interruptions de grossesse au second trimestre.

ABSTRACT

The authors report 48 cases of termination of pregnancy between the 12th and the 20th week using prostaglandins. Two methods were used An injection of 40 mg of Prostaglandin F2 alpha (1) intra-amniotically used on 38 women in group i. 10 patients had 5 mg of 15 (S) 15 methylprostaglandin F2 alpha administered vaginally in group ii. In the first group all women aborted with a mean induction expulsion time of 16 hours and 20 minutes. In the second group 9 women aborted with a mean time of 14 hours and 2 minutes. Side effects were very marked in the second group, whereas they seemed to be acceptable in the first group.