[Clinical importance of chromosomal translocations (author's transl)]. / Klinische Bedeutung chromosomaler Translokationen.
Wien Klin Wochenschr
; 92(11): 395-405, 1980.
Article
em De
| MEDLINE
| ID: mdl-6448518
ABSTRACT
5835 chromosomal analyses were performed between May 1, 1962 and December 31, 1978. We found 68 translocations (1.1%). 36 translocation carriers were identified as being chromosomally balanced, of whom 24 were healthy and 12 clinically abnormal (5 showed centric fusions - 3 x D/D, 2 x D/G - and 7 other chromosomal rearrangements). 32 translocation carriers were chromosomally non-balanced, among them 28 patients with centric fusions (12 x G/G, 2 x D/D, 14 x D/G) and 4 with other rearrangements combined with characteristic clinical features. A review of the chromosomal translocations found in our laboratory is presented. The relation between clinical appearance and chromosomal rearrangement is discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
De
Ano de publicação:
1980
Tipo de documento:
Article