Autoantibodies to nucleosomal proteins: antibodies to HMG-17 in autoimmune diseases.
Science
; 215(4537): 1245-7, 1982 Mar 05.
Article
em En
| MEDLINE
| ID: mdl-6460317
ABSTRACT
The relative amounts of autoantibodies against defined nucleosomal proteins present in serums from patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and mixed connective tissue disease (MCTD) have been examined by an enzyme-linked immunoassay. Autoantibodies to nucleosomal proteins were detected in 45 percent of the patients with SLE, 18 percent of the MCTD patients, and none of the RA patients. The results suggest that, in SLE, antibodies are formed against a subset of nucleosomes which contain protein HMG-17.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Proteínas Cromossômicas não Histona
/
Nucleossomos
Limite:
Humans
Idioma:
En
Ano de publicação:
1982
Tipo de documento:
Article