Dose response of topical carbamylcholine chloride (carbachol) in normotensive and early glaucomatous beagles.
Am J Vet Res
; 45(3): 547-54, 1984 Mar.
Article
em En
| MEDLINE
| ID: mdl-6711984
ABSTRACT
Single-dose loading with a placebo (0.5% methylcellulose) and 0.75%, 1.5%, 2.25%, or 3% carbamylcholine chloride (carbachol) was evaluated in normotensive and glaucomatous Beagles to determine dose response. The 4 carbachol concentrations significantly (P less than 0.05) lowered intraocular pressure and reduced pupil size in the normotensive and early glaucomatous Beagles at most time intervals as compared with base-line values, nontreated fellow eyes, and placebo-treated eyes. There were no significant (P less than 0.24) effects on intraocular pressure or pupil size by unilateral carbachol instillations as compared with base-line values or placebo-treated eyes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carbacol
/
Glaucoma de Ângulo Aberto
/
Doenças do Cão
Limite:
Animals
Idioma:
En
Ano de publicação:
1984
Tipo de documento:
Article