[Ultrastructure of skin fibroblasts in storage diseases (mucopolysaccharidosis types IV and VI)]. / Ul'trastruktura fibroblastov kozhi pri nekotorykh bolezniakh nakopleniia (mukopolisakharidozakh IV i VI tipov).
Tsitol Genet
; 14(5): 21-6, 1980.
Article
em Ru
| MEDLINE
| ID: mdl-6776669
ABSTRACT
Ultrastructure of skin fibroblasts was studied in patients with mucopolysaccharidoses of types IV and VI and their relatives. In MPS VI and keratan-nonexcreting form of MPS IV the cytoplasm of fibroblasts contained numerous vacuoles with material of various electron density. The ultrastructure of cell did not differ from the norm in the keratan-excreting form of MPS IV. Skin fibroblasts from parents and siblings with MPS VI were found to contain a large number of residue bodies. The possible usage of ultrastructural data for early diagnosis of MPS and in medical genetic consultation of families of the patients with MPS is discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Mucopolissacaridoses
/
Mucopolissacaridose IV
/
Mucopolissacaridose VI
Tipo de estudo:
Screening_studies
Limite:
Humans
Idioma:
Ru
Ano de publicação:
1980
Tipo de documento:
Article