Plasma lipids, lipoproteins and apoproteins in a case of apo C-II deficiency.
Clin Chim Acta
; 130(3): 317-27, 1983 Jun 15.
Article
em En
| MEDLINE
| ID: mdl-6872264
ABSTRACT
A new case of apo C-II deficiency is described. The patient had plasma triglyceride levels ranging from 10.2-30.5 mmol/l. Apo C-II deficiency was confirmed by gel electrophoresis, isoelectric focusing and immunochemistry. In this patient plasma lipoproteins were mainly chylomicrons and very low density lipoproteins, LDL and HDL levels being very low. Infusion of normal plasma effectively reduced plasma triglycerides and enhanced low density and high density lipoproteins cholesterol levels. These data suggest that in vivo a precursor-product relationship exists between triglyceride rich lipoproteins and LDL and HDL, and further stress the role of the lipoprotein lipase-apo C-II system in modulating these metabolic interconversions.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Apolipoproteínas
/
Apolipoproteínas C
/
Apoproteínas
/
Lipídeos
/
Lipoproteínas
Limite:
Child
/
Female
/
Humans
Idioma:
En
Ano de publicação:
1983
Tipo de documento:
Article