Fanconi's anemia: ultrastructural observations on erythroblasts.
Ultrastruct Pathol
; 4(2-3): 145-50, 1983.
Article
em En
| MEDLINE
| ID: mdl-6879731
A case of Fanconi's anemia is reported. Particular attention was given to the ultrastructure of the erythroblasts. The main abnormalities are summarized as follows: (1) striking polymorphism of all the erythroblasts, (2) multiple nuclear cisternae showing several breaks, (3) admixture of nucleus and cytoplasm, (4) myelinic figures inside nuclear cisternae and cytoplasm, (5) moth-eaten nucleus, and (6) total absence of normal erythroblasts. These abnormalities were still visible after therapy in spite of clinical and hematologic improvement.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Eritroblastos
/
Eritrócitos
/
Anemia de Fanconi
/
Anemia Aplástica
Tipo de estudo:
Diagnostic_studies
Limite:
Child
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1983
Tipo de documento:
Article