Delayed hypersensitivity in Alzheimer's disease following BCG immunostimulation.
Clin Neuropathol
; 1(4): 169-71, 1982.
Article
em En
| MEDLINE
| ID: mdl-6984828
ABSTRACT
Forty-four patients with Alzheimer's disease were evaluated for delayed hypersensitivity responses using five ubiquitous antigens. Compared with a nondemented age-matched population, these patients evidenced a large number of deficient responses, especially in the zero-response group. Twenty-three patients were randomly selected for immunostimulation using BCG vaccine. The skin tests were repeated 2 weeks after a series of four weekly intradermal injections of BCG. Only 2 of 13 nonresponsive patients failed to convert at least one negative result into a positive response, and seven became normal.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vacina BCG
/
Linfócitos T
/
Demência
/
Doença de Alzheimer
/
Hipersensibilidade Tardia
Limite:
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
1982
Tipo de documento:
Article