Lipid synthesis from the liver in patients with psoriasis.
Arch Dermatol Res
; 268(3): 271-6, 1980.
Article
em En
| MEDLINE
| ID: mdl-7011216
ABSTRACT
In psoriatic patients with hyperlipidemia we studied the hepatic lipid synthesis from (1-(14)C)-acetate in human liver biopsy specimens in vitro by a thin-layer radio-chromatography. In psoriatics type IV (according to Fredrickson) a significant increase in (1-(14)C)-acetate hepatic incorporation especially into phospholipids (25%) and triglycerides (52%) was observed; in type IIb increased lipogenesis was phospholipids (24.5%), free cholesterol (44.4%) and triglycerides (29%). Abnormal lipid metabolism often coexists with glucose intolerance in psoriasis; no correlation between hyperinsulinemia and augmented (1-(14)C)-acetate incorporation into hepatic triglycerides was found.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psoríase
/
Lipídeos
/
Fígado
Limite:
Adult
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
1980
Tipo de documento:
Article