The use of automated headspace gas chromatography for determination of 1,1,1-trichloroethane in rat blood and brain tissue.
Int J Environ Anal Chem
; 12(3-4): 233-9, 1982 Nov.
Article
em En
| MEDLINE
| ID: mdl-7174185
ABSTRACT
1,1,1-trichloroethane in blood and brain tissue from rats which had been artificially ventilated with solvent (8000 ppm) was analysed by automated headspace gas chromatography using a fused silica capillary column. A given concentration of 1,1,1-trichloroethane in the brain could be correlated with a corresponding concentration in the blood; both the uptake and release of the solvent were quicker in blood than in brain. No volatile metabolites of the solvent were found. Automated headspace gas chromatographic analysis is a rapid and sensitive technique for the quantitative registration of volatile organic solvents, e.g. of industrial importance, in body fluids and tissues.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tricloroetanos
/
Química Encefálica
/
Hidrocarbonetos Clorados
Limite:
Animals
Idioma:
En
Ano de publicação:
1982
Tipo de documento:
Article