Elastin metabolism in rodent lung.
Biochim Biophys Acta
; 672(3): 303-6, 1981 Feb 05.
Article
em En
| MEDLINE
| ID: mdl-7213816
ABSTRACT
Data from the in vivo incorporation of [3H]valine into fractions of elastin obtained from rat or mouse lung suggest that postnatal lung elastin synthesis occurs predominantly in the first 1 to 2 weeks of life. Very little [3H]valine was incorporated into lung elastin obtained from adult animals. When lung elastin from neonatal mice was radiochemically labelled with [14C]lysine as a single pulse, it was observed that the specific activity of the elastin expressed as the total dpm values as 14C per mg was not significantly altered over a 6 month period. Elastin appears to turn over very slowly in mouse lung with half-life best estimated in years.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Elastina
/
Pulmão
Limite:
Animals
Idioma:
En
Ano de publicação:
1981
Tipo de documento:
Article