Characterization of surface antigens of transplantable melanomas in hamster on the basis of the macrophage migration inhibition test.

ABSTRACT

Migration of peritoneal macrophages and macrophages isolated from spleen of hamsters with transplanted melanotic melanoma in presence of amelanotic melanoma cells as an antigen was studied. Furthermore, migration of macrophages in hamsters grafted with amelanotic melanoma in presence of melanotic melanoma cells as an antigen was determined. In both cases, inhibition of migration of macrophages was not observed which suggests that both melanoma lines do not have common antigens but individually specific ones.