An endothelial cell-derived growth factor.
J Cell Biol
; 85(2): 467-72, 1980 May.
Article
em En
| MEDLINE
| ID: mdl-7372716
ABSTRACT
Cell-free plasma-derived serum (PDS) is deficient in the platelet-derived growth factor and will not support the growth of 3T3 cells, fibroblasts, or smooth muscle cells. However, when PDS-containing medium is preincubated with endothelial cells, the medium becomes modified so that it will support growth. The activity produced by the endothelial cells results from a polypeptide of 10,000 to 30,000 daltons which has several features that differ from those of the platelet-derived growth factor, including heat instability and lack of adsorption to CM Sephadex.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Substâncias de Crescimento
/
Endotélio
Limite:
Animals
Idioma:
En
Ano de publicação:
1980
Tipo de documento:
Article