Angiogenesis inhibition: a review.
Pharmacol Ther
; 63(3): 265-311, 1994 Sep.
Article
em En
| MEDLINE
| ID: mdl-7530374
In this review we discuss the concept of anti-angiogenesis, which is the inhibition of neovascularization. Anti-angiogenic agents are viewed from the standpoint of their effect on various elements of the angiogenic process, including induction of vascular discontinuity, endothelial cell movement, endothelial cell proliferation, and three-dimensional restructuring of patent vessels. An effort is made to place the many different approaches to anti-angiogenesis research into a comprehensible structure, in order to identify problems of evaluation and interpretation, thereby providing a clearer basis for determining promising and needed directions for further investigation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neovascularização Patológica
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1994
Tipo de documento:
Article